Endocrine Abstracts

Recently we have completed steroid metabolomic study including unconjugated (n=39) and conjugated steroids (n=30) in maternal and fetal body fluids using GC-MS method with two separate multicomponent analyses (for unconjugated steroids and steroid polar conjugates). Our previous data indicate that primarily oxidative isoforms of pluripotent 17β-hydroxysteroid dehydrogenases and aldoketoreductases in placental tissue close to the fetal compartment convert 3&#...

Recently we demonstrated a close correlation between the gestational age (GA) and steroid metabolome in maternal and fetal body fluids using multivariate models including both unconjugated (n=39) and conjugated steroids (n=30) that were measured by GC-MS method including two separate multicomponent analyses (for unconjugated steroids and steroid polar conjugates). We focused on the comparison of the predictive value of the levels of unconjugated steroids alone, c...